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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1989-7-28
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pubmed:abstractText |
Interleukin 6 (IL-6) production from synovial tissues of various diseases was examined. Augmented IL-6 production was found in inflammatory synovium not only in RA but also in other kinds of synovitis, including psoriatic arthritis and Behçet's disease. Increased amounts of IL-6-mRNA were detected in rheumatoid synovium using a dot blot hydridization technique. Furthermore, there was a positive correlation between IL-6 production and accumulation of plasma cells in the synovium. These findings suggest that IL-6 plays an important role not only in immune response but also in active inflammation in various kinds of synovitis.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0090-1229
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
52
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
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pubmed:pagination |
238-47
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2786784-Adult,
pubmed-meshheading:2786784-Aged,
pubmed-meshheading:2786784-Arthritis, Rheumatoid,
pubmed-meshheading:2786784-Female,
pubmed-meshheading:2786784-Humans,
pubmed-meshheading:2786784-Interleukin-1,
pubmed-meshheading:2786784-Interleukin-6,
pubmed-meshheading:2786784-Interleukins,
pubmed-meshheading:2786784-Male,
pubmed-meshheading:2786784-Middle Aged,
pubmed-meshheading:2786784-RNA, Messenger,
pubmed-meshheading:2786784-Synovial Membrane,
pubmed-meshheading:2786784-Synovitis
|
pubmed:year |
1989
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pubmed:articleTitle |
Constitutive production of interleukin 6/B cell stimulatory factor-2 from inflammatory synovium.
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pubmed:affiliation |
Division of Clinical Immunology, Tokyo Women's Medical College, Japan.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|