Linked Life Data

2786643

Source:http://linkedlifedata.com/resource/pubmed/id/2786643

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
13
pubmed:dateCreated
1989-7-25
pubmed:abstractText
The authors have re-examined the skeletal distribution of Paget's disease of bone by means of radionuclide bone scanning performed in 170 untreated pagetic subjects (93 men, 77 women). 863 high uptake foci were detected. The finding that 8.3 p. 100 of the sites revealed by scanning were not visible on X-ray films shows that the disease is underdetected by standard radiography. Peripheral foci in the feet and hands were discovered in more than a quarter of the patients. There was a significant positive correlation between skeletal extension index on the one hand and plasma alkaline phosphatase and hydroxyprolinuria levels on the other hand, these markers being normal in about 7 p. 100 of the cases. Over two-thirds of the foci detected (69 p. 100) were asymptomatic. The skeletal extension index did not increase with age. Serum calcitonin is not a sensitive marker of the increased bone formation characteristic of Paget's disease, and it has little practical value to evaluate the effects of treatments.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
F
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0035-2640
pubmed:author
pubmed:issnType
Print
pubmed:day
27
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1125-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Skeletal distribution and biological markers of Paget's disease].
pubmed:publicationType
Journal Article, English Abstract