Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1989-7-14
|
pubmed:abstractText |
The serum of children with untreated hemophagocytic syndromes contains elevated levels (23,600 to 75,200 U/mL) of soluble interleukin-2 receptor (SIL2R) that returns toward normal with clinical improvement. These levels are in excess of levels previously reported for benign conditions. They are as high as levels reported for HTLV-1-associated adult T-cell leukemia (HATL) and hairy cell leukemia (HCL) in adults and some children with poor-prognosis non-T, non-B, acute lymphoblastic leukemia (ALL). Serum SIL-2R is a marker of disease activity that has the potential to identify infants at risk for the inherited form of the disease before the disease is clinically expressed.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0006-4971
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
73
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2128-32
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:2786434-Adolescent,
pubmed-meshheading:2786434-Child,
pubmed-meshheading:2786434-Child, Preschool,
pubmed-meshheading:2786434-Humans,
pubmed-meshheading:2786434-Infant,
pubmed-meshheading:2786434-Infant, Newborn,
pubmed-meshheading:2786434-Infectious Mononucleosis,
pubmed-meshheading:2786434-Lymphatic Diseases,
pubmed-meshheading:2786434-Macrophages,
pubmed-meshheading:2786434-Phagocytosis,
pubmed-meshheading:2786434-Placenta,
pubmed-meshheading:2786434-Receptors, Interleukin-2,
pubmed-meshheading:2786434-Syndrome
|
pubmed:year |
1989
|
pubmed:articleTitle |
Elevated soluble interleukin-2 receptor in childhood hemophagocytic histiocytic syndromes.
|
pubmed:affiliation |
Department of Pediatrics, Howard Hughes Medical Institute, New Haven, CT 06510.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|