| pubmed-article:2785762 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0026724 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0567416 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0026948 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0596901 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0003250 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C1706089 | lld:lifeskim |
| pubmed-article:2785762 | lifeskim:mentions | umls-concept:C0246576 | lld:lifeskim |
| pubmed-article:2785762 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:2785762 | pubmed:dateCreated | 1989-6-20 | lld:pubmed |
| pubmed-article:2785762 | pubmed:abstractText | Twenty-eight cases of cutaneous T cell lymphomas of mycosis fungoides type, 8 of which showed a marked epidermotropism, were investigated for their reactivity with the monoclonal antibody HML-1. This reagent selectively recognizes human benign and malignant intestinal T lymphocytes, but not benign or malignant lymph node T cells. In all cases, the majority of nonepithelium-associated T cells present in the corium were HML-1 negative. In the eight cases with marked epidermotropism, the intraepidermal (IED) T cells were HML-1 positive in three cases, and HML-1 negative in the remaining five cases. The HML-1 positive IED T cells tended to be localized preferentially in the basal layers, whereas the HML-1 negative IED T cells were more diffusely distributed throughout all epidermal cell layers or formed intra-epidermal aggregates. These findings provide further evidence that mycosis fungoides is not a single entity, but represents a group of neoplasms originating from different T cell subsets that have in common their tropism to epidermis and/or dermis, and thus have a similar clinical presentation. | lld:pubmed |
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| pubmed-article:2785762 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2785762 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2785762 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:2785762 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2785762 | pubmed:month | May | lld:pubmed |
| pubmed-article:2785762 | pubmed:issn | 0002-9440 | lld:pubmed |
| pubmed-article:2785762 | pubmed:author | pubmed-author:Braun-FalcoOO | lld:pubmed |
| pubmed-article:2785762 | pubmed:author | pubmed-author:SteinHH | lld:pubmed |
| pubmed-article:2785762 | pubmed:author | pubmed-author:SperlingMM | lld:pubmed |
| pubmed-article:2785762 | pubmed:author | pubmed-author:KaudewitzPP | lld:pubmed |
| pubmed-article:2785762 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2785762 | pubmed:volume | 134 | lld:pubmed |
| pubmed-article:2785762 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2785762 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2785762 | pubmed:pagination | 955-60 | lld:pubmed |
| pubmed-article:2785762 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2785762 | pubmed:meshHeading | pubmed-meshheading:2785762-... | lld:pubmed |
| pubmed-article:2785762 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2785762 | pubmed:articleTitle | Reactivity of T cells in mycosis fungoides exhibiting marked epidermotropism with the monoclonal antibody HML-1 that defines a membrane molecule on human mucosal lymphocytes. | lld:pubmed |
| pubmed-article:2785762 | pubmed:affiliation | Institut für Pathologie, Klinikum Steglitz, Freie Universität Berlin, Federal Republic of Germany. | lld:pubmed |
| pubmed-article:2785762 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2785762 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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