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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1989-6-15
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pubmed:abstractText |
We compared the relative efficacy of medium- and long-chain triglycerides and dextrose on intestinal adaptation. Parenterally nourished rats received an isocaloric luminal infusion of one of these three substrates for 1 wk into either the jejunum or the ileum. Intestinal mass (mucosal weight and protein content) as well as the in vivo absorption of 5 mM glucose, valine, and aspartic acid were measured. In the jejunum, long-chain triglycerides were the most trophic, whereas in the ileum, long-chain triglycerides and dextrose were equally effective, but significantly more trophic than medium-chain triglycerides. In general, absorptive function was better maintained by dextrose and medium-chain triglycerides than long-chain triglycerides in the jejunum or by dextrose in the ileum. These data demonstrate that the jejunum and ileum respond differently to caloric substrates. Medium-chain triglycerides do not appear to have a clear superiority to long-chain triglycerides or dextrose in producing intestinal adaptation.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Aspartic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Carbohydrates,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/Emulsions,
http://linkedlifedata.com/resource/pubmed/chemical/Fat Emulsions, Intravenous,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids,
http://linkedlifedata.com/resource/pubmed/chemical/Soybean Oil,
http://linkedlifedata.com/resource/pubmed/chemical/Triglycerides,
http://linkedlifedata.com/resource/pubmed/chemical/Valine,
http://linkedlifedata.com/resource/pubmed/chemical/soybean oil, phospholipid emulsion
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1514-20
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:2785468-Adaptation, Physiological,
pubmed-meshheading:2785468-Animals,
pubmed-meshheading:2785468-Aspartic Acid,
pubmed-meshheading:2785468-Dietary Carbohydrates,
pubmed-meshheading:2785468-Dietary Fats,
pubmed-meshheading:2785468-Emulsions,
pubmed-meshheading:2785468-Fat Emulsions, Intravenous,
pubmed-meshheading:2785468-Glucose,
pubmed-meshheading:2785468-Hyperplasia,
pubmed-meshheading:2785468-Ileum,
pubmed-meshheading:2785468-Intestinal Absorption,
pubmed-meshheading:2785468-Intestinal Mucosa,
pubmed-meshheading:2785468-Jejunum,
pubmed-meshheading:2785468-Male,
pubmed-meshheading:2785468-Phospholipids,
pubmed-meshheading:2785468-Rats,
pubmed-meshheading:2785468-Rats, Inbred Strains,
pubmed-meshheading:2785468-Soybean Oil,
pubmed-meshheading:2785468-Triglycerides,
pubmed-meshheading:2785468-Valine
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pubmed:year |
1989
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pubmed:articleTitle |
Comparison of different caloric substrates on intestinal adaptation in the rat.
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pubmed:affiliation |
Division of Gastroenterology and Nutrition, Albert Einstein Medical Center, Philadelphia, Pennsylvania.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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