Linked Life Data

2785230

Source:http://linkedlifedata.com/resource/pubmed/id/2785230

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1989-6-8
pubmed:abstractText
An new latex agglutination system was developed for the detection of occult blood in the feces. Antibodies against human hemoglobin were raised in a goat. Blood in concentrations of 0.1 ml-8.0 ml/100 g feces were detected in vitro. The antibodies were separated and adsorbed to latex particles (0.3 microns). After in vitro standardisation of the new test system we compared the efficacy of the commonly used guaiac slide test for detection of occult blood in the stool (hemoccult-test) with the latex test system. A significant higher sensitivity could be reached with the latex test system. In a clinical study 61 patients were tested. In 31 of them occult blood was found with the latex test system while with the guaiac slide-test system no blood was detected using the same stool specimen. 13 of the 31 patients had a neoplastic lesion of the colon - 4 a colon carcinoma and 9 had adenomatous polyps of the large bowel larger than 5 mm in diameter. In the remaining patients the sources of intestinal bleeding were: upper gastro-intestinal bleeding sources in 8 patients and other colonic bleeding sources like diverticular disease, inflammatory bowel disease, hemorrhoids and a rectal ulcer in 8 patients. In 2 of the 61 patients the latex test was positive without endoscopic significance for the bleeding source.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0023-2173
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
291-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[A new latex agglutination test for the immunologic detection of occult blood in stool].
pubmed:affiliation
I. Medizinische Klinik, St. Markuskrankenhaus, Frankfurt a.M.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract, Research Support, Non-U.S. Gov't