| pubmed-article:2784018 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2784018 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:2784018 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2784018 | lifeskim:mentions | umls-concept:C0007134 | lld:lifeskim |
| pubmed-article:2784018 | lifeskim:mentions | umls-concept:C1522405 | lld:lifeskim |
| pubmed-article:2784018 | lifeskim:mentions | umls-concept:C0205470 | lld:lifeskim |
| pubmed-article:2784018 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:2784018 | lifeskim:mentions | umls-concept:C0205179 | lld:lifeskim |
| pubmed-article:2784018 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2784018 | pubmed:dateCreated | 1989-4-4 | lld:pubmed |
| pubmed-article:2784018 | pubmed:abstractText | Immunologic and antitumor effects of human recombinant interleukin-2 was studied in patients with advanced renal cell carcinoma. Intravenous drip infusion for inpatients or subsequent subcutaneous injection for outpatients at a daily dose of 1 x 10(6) units of interleukin-2 was given over a period varying from twenty-one to two hundred forty days to 13 patients. Natural killer cell activity increased 20 percent or more in 11 of the 13 patients, and lymphokine-activated killer cell activity increased 40 percent or more in 9 of the patients tested. Interleukin-2-receptor positive cells and HLA-DR positive cells in peripheral blood lymphocytes increased in 12 and 11 patients, respectively. Two patients achieved complete response; 1 had a partial response; 6 had no change; and 2 had progressive disease. Two patients were not evaluated because the therapy had been discontinued in less than four weeks. We conclude that low-dose interleukin-2 enhances patients' immunity and has a potential antitumor activity against renal cell carcinoma. | lld:pubmed |
| pubmed-article:2784018 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2784018 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2784018 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2784018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2784018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2784018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2784018 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2784018 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2784018 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:2784018 | pubmed:issn | 0090-4295 | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:TachibanaMM | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:BabaSS | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:UenoMM | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:DeguchiNN | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:HataMM | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:TazakiHH | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:JitsukawaSS | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:MarumoKK | lld:pubmed |
| pubmed-article:2784018 | pubmed:author | pubmed-author:MurakiJJ | lld:pubmed |
| pubmed-article:2784018 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2784018 | pubmed:volume | 33 | lld:pubmed |
| pubmed-article:2784018 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2784018 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2784018 | pubmed:pagination | 219-25 | lld:pubmed |
| pubmed-article:2784018 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:2784018 | pubmed:meshHeading | pubmed-meshheading:2784018-... | lld:pubmed |
| pubmed-article:2784018 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2784018 | pubmed:articleTitle | Immunologic study of human recombinant interleukin-2 (low-dose) in patients with advanced renal cell carcinoma. | lld:pubmed |
| pubmed-article:2784018 | pubmed:affiliation | Department of Urology, School of Medicine, Keio University, Tokyo, Japan. | lld:pubmed |
| pubmed-article:2784018 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2784018 | pubmed:publicationType | Case Reports | lld:pubmed |
| pubmed-article:2784018 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2784018 | lld:pubmed |
