Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1989-3-23
|
| pubmed:abstractText |
Serum levels of soluble interleukin-2 receptors (sIL-2R) were measured in 105 HIV-seropositive individuals simultaneously with T cell subsets and activated T cells (CD3+ and HLA-DR+). Significantly elevated levels of serum sIL-2R were found (564 +/- 259 U/ml versus 258 +/- 87 U/ml in 70 controls, p less than 0.001), as well as increased numbers of activated T cells (mean numbers, 579/microliters in the patients versus 113/microliters in 26 controls, p less than 0.0001). Correlation analysis did not disclose any significant association between elevated sIL-2R and increased activated T cells, nor with decreased CD4+ lymphocytes. These data suggest that sIL-2R in HIV infection do not emanate from activated T cells and are not linked to CD4+ cell loss.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:author | |
| pubmed:volume |
31
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
9-11
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2783774-Adolescent,
pubmed-meshheading:2783774-Adult,
pubmed-meshheading:2783774-Female,
pubmed-meshheading:2783774-HIV Seropositivity,
pubmed-meshheading:2783774-Humans,
pubmed-meshheading:2783774-Leukocyte Count,
pubmed-meshheading:2783774-Lymphocyte Activation,
pubmed-meshheading:2783774-Male,
pubmed-meshheading:2783774-Middle Aged,
pubmed-meshheading:2783774-Receptors, Interleukin-2,
pubmed-meshheading:2783774-Solubility,
pubmed-meshheading:2783774-T-Lymphocytes
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
Elevated serum levels of soluble interleukin-2 receptors in HIV infection: no correlation with activated T cells.
|
| pubmed:affiliation |
Service d'Onco-Hématologie, Hôpital de Hautepierre, Strasbourg, France.
|
| pubmed:publicationType |
Journal Article
|