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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
37
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pubmed:dateCreated |
1989-10-20
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pubmed:abstractText |
Measurement of blood-spot 17-hydroxyprogesterone (17-OHP) concentration was used to identify cases of congenital adrenal hyperplasia (CAH) among patients with inappropriate virilization and/or salt wasting. Between 1978 to 1986 61 cases with 21-hydroxylase deficiency among 707 patients (278 newborns, 204 infants and 225 children) were identified. The incidence of classical CAH was calculated for a seven year prospective trial period using the blood-spot 17-OHP method in selective screening. There were 38 salt-losers and 14 simple virilizers in 968,303 live births giving an incidence of 1 in 18,000 for CAH in the Hungarian population. The use of a central laboratory facility to measure the blood-spot 17-OHP concentrations is proposed as a valuable initial method to investigate patients at risk for CAH in countries where blood steroid assays are not readily available in hospitals.
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pubmed:language |
hun
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0030-6002
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
|
pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
1979-82, 1985-6
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pubmed:dateRevised |
2009-10-21
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pubmed:meshHeading |
pubmed-meshheading:2780047-17-Hydroxycorticosteroids,
pubmed-meshheading:2780047-Adrenal Hyperplasia, Congenital,
pubmed-meshheading:2780047-Child,
pubmed-meshheading:2780047-Child, Preschool,
pubmed-meshheading:2780047-Humans,
pubmed-meshheading:2780047-Hungary,
pubmed-meshheading:2780047-Infant,
pubmed-meshheading:2780047-Infant, Newborn,
pubmed-meshheading:2780047-Mass Screening
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pubmed:year |
1989
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pubmed:articleTitle |
[Screening for congenital adrenal hyperplasia in Hungary].
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pubmed:publicationType |
Journal Article,
English Abstract
|