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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1989-10-19
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pubmed:abstractText |
Allergic reactions after insect stings may have a delayed onset, differing from the usual immediate anaphylactic pattern. Ten patients, aged 6 to 78 years, had allergic reactions 1 to 2 weeks after an insect sting. Six patients had had multiple stings preceding the reaction. In two instances, immediate anaphylaxis also occurred. Four of the 10 patients had serum sickness-type reactions; two other patients had more severe anaphylactic symptoms, including throat edema. All patients in this group had venom-specific IgE; four of the 10 patients had serum venom-specific IgG. Eight patients subsequently received venom immunotherapy (VIT). There have been no reactions from seven re-stings. Five patients had generalized hives starting 6 to 24 hours after an insect sting. All patients in this group had venom-specific IgE; three patients have received VIT. Two other patients developed hives, one with throat edema 3 days after an insect sting. Both patients had high titers of serum venom-specific IgE; neither patient has received VIT, one patient because of extreme sensitivity. These observations suggest that after an insect sting, patients may develop delayed-onset allergic symptoms that range from typical anaphylaxis to serum sickness and are mediated by venom-specific IgE. VIT is recommended for patients with these reactions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0091-6749
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
331-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2778239-Adult,
pubmed-meshheading:2778239-Aged,
pubmed-meshheading:2778239-Anaphylaxis,
pubmed-meshheading:2778239-Animals,
pubmed-meshheading:2778239-Bee Venoms,
pubmed-meshheading:2778239-Bees,
pubmed-meshheading:2778239-Child,
pubmed-meshheading:2778239-Female,
pubmed-meshheading:2778239-Humans,
pubmed-meshheading:2778239-Hypersensitivity, Delayed,
pubmed-meshheading:2778239-Immunoglobulin E,
pubmed-meshheading:2778239-Immunoglobulin G,
pubmed-meshheading:2778239-Immunotherapy,
pubmed-meshheading:2778239-Insect Bites and Stings,
pubmed-meshheading:2778239-Male,
pubmed-meshheading:2778239-Middle Aged,
pubmed-meshheading:2778239-Radioallergosorbent Test,
pubmed-meshheading:2778239-Serum Sickness,
pubmed-meshheading:2778239-Skin Tests,
pubmed-meshheading:2778239-Time Factors
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pubmed:year |
1989
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pubmed:articleTitle |
Late-onset allergic reactions, including serum sickness, after insect stings.
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pubmed:affiliation |
Buffalo General Hospital, Department of Medicine, State University of New York 14203.
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pubmed:publicationType |
Journal Article
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