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pubmed-article:2777758pubmed:abstractTextSimian virus 40 large tumor (T) antigen stimulates transcription from the SV40 late promoter and some cellular genes. We report here the novel finding that purified T antigen preferentially stimulates transcription from the human heat shock protein 70 promoter in an in vitro transcription system. T antigen is thus capable of stimulating transcription by a process that does not require synthesis of other proteins and that may involve a direct interaction with preexisting cellular factors.lld:pubmed
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pubmed-article:2777758pubmed:articleTitleStimulation of the human heat shock protein 70 promoter in vitro by simian virus 40 large T antigen.lld:pubmed
pubmed-article:2777758pubmed:affiliationDepartment of Molecular Biology, Massachusetts General Hospital, Boston 02114.lld:pubmed
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