|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
27
|
|
pubmed:dateCreated |
1989-10-25
|
|
pubmed:abstractText |
Simian virus 40 large tumor (T) antigen stimulates transcription from the SV40 late promoter and some cellular genes. We report here the novel finding that purified T antigen preferentially stimulates transcription from the human heat shock protein 70 promoter in an in vitro transcription system. T antigen is thus capable of stimulating transcription by a process that does not require synthesis of other proteins and that may involve a direct interaction with preexisting cellular factors.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0021-9258
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
25
|
|
pubmed:volume |
264
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
16160-4
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:2777758-Animals,
pubmed-meshheading:2777758-Antigens, Polyomavirus Transforming,
pubmed-meshheading:2777758-Cells, Cultured,
pubmed-meshheading:2777758-Gene Expression Regulation,
pubmed-meshheading:2777758-Genes,
pubmed-meshheading:2777758-HeLa Cells,
pubmed-meshheading:2777758-Heat-Shock Proteins,
pubmed-meshheading:2777758-Humans,
pubmed-meshheading:2777758-Mice,
pubmed-meshheading:2777758-Mice, Inbred BALB C,
pubmed-meshheading:2777758-Plasmids,
pubmed-meshheading:2777758-Promoter Regions, Genetic,
pubmed-meshheading:2777758-Transcription, Genetic,
pubmed-meshheading:2777758-Transfection
|
|
pubmed:year |
1989
|
|
pubmed:articleTitle |
Stimulation of the human heat shock protein 70 promoter in vitro by simian virus 40 large T antigen.
|
|
pubmed:affiliation |
Department of Molecular Biology, Massachusetts General Hospital, Boston 02114.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
