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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-10-6
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pubmed:abstractText |
Casein kinase II (CKII) activity in colorectal tumours was compared before and after heterotransplantation onto nude mice. The test revealed that the enzyme activity was about two-fold enhanced in the tumours isolated from the nude mice when compared to the respective primary tumours from which they were derived. Immunoblots using a polyclonal CKII-specific antibody showed that the increase of activity was due to a higher expression of the enzyme. Immunohistochemical studies on cross sections of nude mouse tumours showed that most of the CKII molecules were located at the peripheral part of the tumour; the central part did not show intense CKII-specific staining.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
163
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
635-41
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:2775290-Animals,
pubmed-meshheading:2775290-Carcinoma,
pubmed-meshheading:2775290-Casein Kinases,
pubmed-meshheading:2775290-Colonic Neoplasms,
pubmed-meshheading:2775290-Humans,
pubmed-meshheading:2775290-Immunohistochemistry,
pubmed-meshheading:2775290-Mice,
pubmed-meshheading:2775290-Mice, Nude,
pubmed-meshheading:2775290-Neoplasm Transplantation,
pubmed-meshheading:2775290-Protein Kinases
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pubmed:year |
1989
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pubmed:articleTitle |
Characterization of casein kinase II in human colonic carcinomas after heterotransplantation into nude mice.
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pubmed:affiliation |
Institut für Humangenetik, Universität des. Saarlandes, Homburg, FRG.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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