Linked Life Data

2773147

Source:http://linkedlifedata.com/resource/pubmed/id/2773147

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
34
pubmed:dateCreated
1989-10-5
pubmed:abstractText
A review is presented of antiglomerular basal membrane antibody-mediated glomerulonephritis (anti-GBM-Ab-nephritis) which constitutes 2-5% of all cases of acute glomerulonephritis. The disease frequently commences in the age group 20-30 years but may be encountered in all age groups, in women particularly at 60 years of age. The disease is due to autoantibodies (IgG) to the basal membranes in the glomeruli and alveoli. Deposition of IgG with C3 precipitates an inflammatory reaction which causes renal and possibly also pulmonary damage. It is possible to demonstrate anti-GMB-antibodies in the blood and, by means of immunofluorescence microscopy, these and C3 may be demonstrated in the basal membranes in the glomeruli and alveoli. The disease is still serious but introduction of immune-suppressive treatment and plasmapheresis has improved the prognosis considerably.
pubmed:language
dan
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0041-5782
pubmed:author
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
151
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2141-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Goodpasture's syndrome. Antiglomerular basal membrane antibody-mediated glomerulonephritis].
pubmed:publicationType
Journal Article, English Abstract, Case Reports