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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1989-9-27
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pubmed:abstractText |
Possible hepatitis B immunization of all newborns, regardless of the mother's HBsAg status, is a strategy under consideration for selected hyperendemic areas in Italy. Sardinia is one such area. However, in 1987 in Sardinia, the prevalence of hepatitis B markers in children under 11 years was estimated at 1.7% and the prevalence of hepatitis B surface antigen (HBsAg) at 0.2%. A much higher prevalence of HBsAg was recently observed among adults in this area: 8.7% among men and 5.2% among pregnant women. This contrasting pattern is unlikely to be due to bias: the sampling procedures adopted were appropriate and the percentage of refusals was very low (2.2%). The observed low hepatitis B marker prevalence in young age groups might be the result of a cohort effect due to the improved socio-economic conditions and changes in behaviour that have occurred in Sardinia over the last few years. The finding of only 3 HBsAg+ individuals out of 1,826 children tested, in spite of the 5.2% HBsAg prevalence among pregnant women in that region, is probably attributable to the low proportion of HBeAg positive individuals among the HBsAg+ carrier mothers in this area. At present, immunization of all newborns in Sardinia cannot be recommended.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0393-2990
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
202-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2767229-Age Factors,
pubmed-meshheading:2767229-Child,
pubmed-meshheading:2767229-Child, Preschool,
pubmed-meshheading:2767229-Demography,
pubmed-meshheading:2767229-Female,
pubmed-meshheading:2767229-Hepatitis B,
pubmed-meshheading:2767229-Hepatitis B Core Antigens,
pubmed-meshheading:2767229-Hepatitis B Surface Antigens,
pubmed-meshheading:2767229-Humans,
pubmed-meshheading:2767229-Immunization,
pubmed-meshheading:2767229-Infant,
pubmed-meshheading:2767229-Italy,
pubmed-meshheading:2767229-Male,
pubmed-meshheading:2767229-Serologic Tests
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pubmed:year |
1989
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pubmed:articleTitle |
Hepatitis B virus infection in children in Sardinia, Italy.
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pubmed:affiliation |
Laboratorio di Epidemiologia - Istituto Superiore di Sanità, Rome, Italy.
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pubmed:publicationType |
Journal Article
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