Linked Life Data

2766921

Source:http://linkedlifedata.com/resource/pubmed/id/2766921

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-9-28
pubmed:abstractText
Latency to the loss of righting reflex and sleeping time after ketamine were measured in 261 rats aged 7, 12, 18, 25 and 90 days. The sensitivity to ketamine was highest in 7-day-old animals and decreased with age. In the youngest group rats slept after the 20-mg/kg dose whereas not all adult animals lost their righting ability after a dose of 160 mg/kg. Electrocorticographic (ECoG) study demonstrated an age dependence of changes induced by ketamine. The youngest group exhibited only suppression of the originally discontinuous ECoG whereas signs of slow-wave sleep or depression appeared in older rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0379-8305
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
179-87
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Ontogenetic development of ketamine-induced sleeping time and electrocorticographic changes in rats.
pubmed:affiliation
Institute of Physiology, Faculty of General Medicine, Charles University, Prague, Czechoslovakia.
pubmed:publicationType
Journal Article