Linked Life Data

2762734

Source:http://linkedlifedata.com/resource/pubmed/id/2762734

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-9-12
pubmed:abstractText
Cytidine diphosphocholine (CDC) was incorporated into unilamellar egg lecithin liposomes with a yield of 23% and subsequently administered to rats by intracardiac injection. Unlike free CDC, 0.2% of which was absorbed by the brain, 21% of the CDC-liposomes was absorbed by the brain, while their relative distribution among brain phospholipids was similar. The changes in blood concentration and brain content of CDC, with and without liposomes, were measured at different times after administration. The CDC-liposome association significantly increased, unlike CDC alone, the levels of dopamine catabolites in the striatum of rats treated with haloperidol (0.15 mg/Kg/die) after 5 days of intravenous administration (20 mg/Kg/die).
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0035-6344
pubmed:author
pubmed:issnType
Print
pubmed:volume
59
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
26-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Preparation, properties and therapeutic potential of cytidine diphosphocholine incorporated into liposomes].
pubmed:publicationType
Journal Article, English Abstract, Research Support, Non-U.S. Gov't