|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
1989-9-12
|
|
pubmed:abstractText |
The virally transduced oncogene v-cbl transforms fibroblasts in vitro and induces early B-cell-lineage lymphomas in vivo. A series of probes derived from a molecular clone of v-cbl were used to map related sequences in the mouse genome. Analyses of Chinese hamster x mouse somatic-cell hybrids showed that two related genes, cbl-1 and cbl-2, were located on chromosomes 6 and 9, respectively. Restriction enzyme studies of DNA from hybrid cells containing either chromosome 6 or 9 suggested that cbl-1 resembles v-cbl and may be a processed gene, whereas cbl-2 has a complex genomic structure. Analyses of Mus domesticus/M. spretus interspecific backcross mice showed that Cbl-1 maps between the immunoglobulin kappa light chain and T-cell receptor beta chain loci and that Cbl-2 is tightly linked to Thy-1.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-16453485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2419762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2784003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2820874,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2851124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2863819,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2869046,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2963140,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2990725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-2995250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-3014001,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-3258175,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-3692486,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-3917311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-6297784,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-6316155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-6462246,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2760978-6691137
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0022-538X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
63
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3678-82
|
|
pubmed:dateRevised |
2010-9-10
|
|
pubmed:meshHeading |
|
|
pubmed:year |
1989
|
|
pubmed:articleTitle |
Identification of two murine loci homologous to the v-cbl oncogene.
|
|
pubmed:affiliation |
Laboratory of Immunopathology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
