| pubmed-article:2753020 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2753020 | lifeskim:mentions | umls-concept:C0007450 | lld:lifeskim |
| pubmed-article:2753020 | lifeskim:mentions | umls-concept:C0027358 | lld:lifeskim |
| pubmed-article:2753020 | lifeskim:mentions | umls-concept:C1720776 | lld:lifeskim |
| pubmed-article:2753020 | lifeskim:mentions | umls-concept:C0234112 | lld:lifeskim |
| pubmed-article:2753020 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2753020 | pubmed:dateCreated | 1989-8-31 | lld:pubmed |
| pubmed-article:2753020 | pubmed:abstractText | The effect of repetitive administration of naloxone on the development of massed amygdaloid kindling in 'encéphale isolé' cats was studied. Electrical amygdaloid kindling was carried out with a 15 min inter-stimulus interval (ISI) in a control situation with intravenous (i.v.) naloxone administration (2, 4, and 8 mg/kg), 5 min prior to amygdaloid stimulation. It was found that it was possible to complete the amygdaloid kindling process in the encéphale isolé preparation reaching generalized electrographic tonic-clonic self-sustained seizures. The enhancement of the duration, frequency, and propagation of the after-discharge (AD) was accentuated by naloxone which also induced a progressive amplitude increment of the first potential evoked by the onset of the tetanus. The number of trials needed to achieve seizure generalization was reduced in dose-dependent manner by naloxone. The ability of naloxone to accelerate the development of amygdaloid kindling may be related to an inhibitory role of opioid peptides in this process. | lld:pubmed |
| pubmed-article:2753020 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2753020 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2753020 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2753020 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2753020 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2753020 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2753020 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2753020 | pubmed:issn | 0920-1211 | lld:pubmed |
| pubmed-article:2753020 | pubmed:author | pubmed-author:CalvoJ MJM | lld:pubmed |
| pubmed-article:2753020 | pubmed:author | pubmed-author:Fernández-Gua... | lld:pubmed |
| pubmed-article:2753020 | pubmed:author | pubmed-author:PellicerFF | lld:pubmed |
| pubmed-article:2753020 | pubmed:author | pubmed-author:GutiérrezRR | lld:pubmed |
| pubmed-article:2753020 | pubmed:author | pubmed-author:RochaLL | lld:pubmed |
| pubmed-article:2753020 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2753020 | pubmed:volume | 4 | lld:pubmed |
| pubmed-article:2753020 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2753020 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2753020 | pubmed:pagination | 55-62 | lld:pubmed |
| pubmed-article:2753020 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:meshHeading | pubmed-meshheading:2753020-... | lld:pubmed |
| pubmed-article:2753020 | pubmed:articleTitle | Massed amygdaloid kindling in encéphale isolé cats: its facilitation by naloxone. | lld:pubmed |
| pubmed-article:2753020 | pubmed:affiliation | División de Investigaciones en Neurociencias, UNAM, Mexico. | lld:pubmed |
| pubmed-article:2753020 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2753020 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
