Linked Life Data

2752366

Source:http://linkedlifedata.com/resource/pubmed/id/2752366

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1989-9-1
pubmed:abstractText
The elemental content of the anterior and posterior cortex and of the nucleus of the rat eye lens, and the changes occurring as a function of age, were investigated by energy-dispersive X-ray microanalysis of cryostat sections. In contrast to most other cells investigated by this technique, the main element detectable in the lens was sulfur, not phosphorus. This is likely to be due to the lack of cell organelles and of nucleic acids in the lens cells. Up to 19 months of age, the concentrations of Na, Cl and K are much lower in the nucleus than in the cortex, whereas the concentration of S is highest in the cortex. At 25 months the differences in elemental content between nucleus and cortex, while still present, are less pronounced. The age-related changes in ion content are rather complex and appear to be different for different parts of the lens. In general, the ion content of the lens increases with age. In the nucleus, the concentration of K increases gradually with age, whereas the Na concentration only appears to increase after 19 months. The Na/K ratio in the lens nucleus is lower in the oldest groups. The Ca concentration increases with age in the nucleus and the posterior cortex, but not in the anterior cortex.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1122-9497
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
391-6
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Distribution of diffusible ions in the aging rat lens. An X-ray microanalytical investigation.
pubmed:affiliation
Institute of Clinical Electron Microscopy, University of Bologna, Italy.
pubmed:publicationType
Journal Article