Linked Life Data

2752297

Source:http://linkedlifedata.com/resource/pubmed/id/2752297

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1989-8-31
pubmed:abstractText
Single-unit recordings were made from neurones in the zona incerta (ZI) of conscious sheep in response to the sight/visual approach or ingestion of various foods, salts and water. Animals were given parotid fistulae so that effects of sodium appetite, induced by not replacing the sodium lost in the saliva, could be assessed. When sodium depletion was prevented by giving the animals 1% sodium bicarbonate in their drinking water, the majority of cells (45 out of 49) responded most strongly to the sight or visual approach of food compared to water or salt. Four cells responded best to the sight of water, but none to the sight of salt and salt solutions. When a sodium appetite was stimulated, by removing the 1% sodium bicarbonate replacement for 4-6 days, there was a significant change in response profiles of ZI cells. The majority of cells responded most strongly to the sight of salts or salt solutions (35 out of 49) and significantly fewer cells responded most strongly to food (8 out of 49). The number of cells responding primarily to water was not affected (6 out of 49). For 3 cells responding to salts it was shown that, after repeated ingestion of salt over several hours, food became a more potent stimulus. A similar decreased response to foods during sodium depletion, and an increased one to salts, was seen in ZI cells which responded to the ingestion of both solids and liquids. These results show that changing an animal's motivational state produces significant changes in the responses of cells in the ZI responding to the sight or visual approach of substances.(ABSTRACT TRUNCATED AT 250 WORDS)
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
492
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
The effects of sodium appetite on the responses of cells in the zona incerta to the sight or ingestion of food, salt and water in sheep.
pubmed:affiliation
A.F.R.C. Institute of Animal Physiology and Genetics and Research, Babraham, Cambridge, U.K.
pubmed:publicationType
Journal Article