|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1989-8-21
|
|
pubmed:abstractText |
Stimulating effect of cyclosporine on growth and invasiveness of tumor xenographts was studied on a model of rat solid sarcoma M-1 transplanted under the kidney capsule in mice. Cyclosporine was administered subcutaneously in a dose of 25 or 75 mg/kg on days 1-7. The stimulating effect of cyclosporine was directly associated with the immunodepressant dose and accompanied by a decrease in the thymus weight. With using cyclosporine the model of xenographts under the kidney capsule can be of value in screening cytostatics and immunomodulators.
|
|
pubmed:language |
rus
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0235-2990
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
34
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
280-2
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:2751385-Animals,
pubmed-meshheading:2751385-Cyclosporins,
pubmed-meshheading:2751385-Female,
pubmed-meshheading:2751385-Graft Survival,
pubmed-meshheading:2751385-Growth Substances,
pubmed-meshheading:2751385-Kidney,
pubmed-meshheading:2751385-Kidney Neoplasms,
pubmed-meshheading:2751385-Mice,
pubmed-meshheading:2751385-Neoplasm Transplantation,
pubmed-meshheading:2751385-Rats,
pubmed-meshheading:2751385-Sarcoma, Experimental,
pubmed-meshheading:2751385-Soft Tissue Neoplasms,
pubmed-meshheading:2751385-Stimulation, Chemical,
pubmed-meshheading:2751385-Time Factors,
pubmed-meshheading:2751385-Transplantation, Heterologous
|
|
pubmed:year |
1989
|
|
pubmed:articleTitle |
[Effect of cyclosporin on tumor xenotransplantation under the renal capsule in mice].
|
|
pubmed:publicationType |
Journal Article,
English Abstract
|
