Linked Life Data

2750596

Source:http://linkedlifedata.com/resource/pubmed/id/2750596

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-8-22
pubmed:abstractText
We previously reported a cell culture system in artificial collagen gel as a model system of vitreous contraction. In this report, the epithelium cultured in the collagen gel elongated and induced gel contraction. The motile cytoskeletal components were thought to be important for morphological changes of the cells and the gel contraction. In order to examine the relationship between the cytoskeletal components and morphological changes of the cells and gel contraction, colchicine and cytochalasin B, known to be inhibitors for microtubules and microfilaments respectively, were added to the gels and the culture media. Bovine lens epithelia were cultured in the gels and the media containing 0-1000 nM colchicine or 0-10 microM cytochalasin B. Both inhibitors arrested the elongation of the cells and the contraction of the gels. These results suggested that the cell movement caused by the functions of microtubules and microfilaments were related to the vitreous contraction.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0029-0203
pubmed:author
pubmed:issnType
Print
pubmed:volume
93
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-8
pubmed:dateRevised
2011-7-28
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[The role of the cytoskeletal components in cell culture in collagen gel as a model system of vitreous contraction].
pubmed:publicationType
Journal Article, English Abstract