Linked Life Data

2738769

Source:http://linkedlifedata.com/resource/pubmed/id/2738769

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-7-28
pubmed:abstractText
In isolated chondrocytes from the growth plate, there is an increase in both the cytosolic ionized calcium concentration and in total cell calcium content as the cells approach the mineralization front. The reserve zone chondrocytes have a cytosolic ionized calcium concentration, [Ca2+]i, of 124 +/- 23 nM and a total cell calcium content, CaT, of 12.8 +/- 6.8 nmol/mg cell protein. Proliferative zone chondrocytes have a [Ca2+]i of 172 +/- 29 nM and a CaT of 16.1 +/- 11.8 nmol/mg cell protein. Hypertrophic zone chondrocytes have a [Ca2+]i of 273 +/- 49 nM and a CaT of 35.8 +/- 16 nmol/mg protein. Chondrocytes isolated from the entire growth plate have a [Ca2+]i of 132 +/- 29 nM and a CaT of 13.2 +/- 2.5 nmol/mg cell protein. Chondrocytes isolated from noncalcifying hyaline cartilage have a [Ca2+]i of 85 +/- 10 nM and a CaT of 11.5 +/- 1.4 nmol/mg cell protein. There appears to be a correlation between intracellular calcium accumulation, an increase in the intracellular ionized calcium concentration, and the process of cartilage matrix mineralization.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0736-0266
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
511-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Cytosolic ionized calcium concentration in isolated chondrocytes from each zone of the growth plate.
pubmed:affiliation
McKay Laboratory of Orthopaedic Research, University of Pennsylvania School of Medicine, Philadelphia 19104.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.