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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1989-8-8
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pubmed:abstractText |
We introduce two new nondigestible solid markers for gastrointestinal transit measurements. One is technetium-99m-labeled cellulose fiber [99mTc]CF, the other is indium-111-labeled plastic particles [111In]PP of 2- to 3-mm diameter. In six healthy male volunteers gastric emptying and small intestinal transit of the two markers were obtained simultaneously. Large intestinal transit of [111In]PP was also obtained. Technetium-99m CF had acceptable stability properties in the proximal gastrointestinal segments. Indium-111 PP was almost completely stable in all segments. Mean gastric emptying time was 1.13 +/- 0.24 hr (mean +/- s.d.) for [99mTc]CF and 1.94 +/- 0.78 hr for [111In]PP. The difference was significant (p less than 0.05). Mean small intestinal transit time was 3.85 +/- 0.61 hr (mean +/- s.d.) for [99mTc]CF and 4.03 +/- 0.34 hr for [111In]PP. The difference was not significant (p less than 0.5). Mean large intestinal transit time of [111In]PP was 23 +/- 11 hr (mean +/- s.d.). We also suggest a simple deconvolution principle for the interpretation of the small intestinal and the large intestinal transit data.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0161-5505
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
402-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2738668-Adult,
pubmed-meshheading:2738668-Cellulose,
pubmed-meshheading:2738668-Gastric Emptying,
pubmed-meshheading:2738668-Gastrointestinal Transit,
pubmed-meshheading:2738668-Humans,
pubmed-meshheading:2738668-Indium Radioisotopes,
pubmed-meshheading:2738668-Male,
pubmed-meshheading:2738668-Microspheres,
pubmed-meshheading:2738668-Polystyrenes,
pubmed-meshheading:2738668-Technetium
|
pubmed:year |
1989
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pubmed:articleTitle |
Gastrointestinal transit of technetium-99m-labeled cellulose fiber and indium-111-labeled plastic particles.
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pubmed:affiliation |
Department of Clinical Physiology and Nuclear Medicine, Rigshospitalet, Copenhagen, Denmark.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|