Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1989-7-28
|
| pubmed:abstractText |
Cytosol from untreated cells and a detergent extract of the particulate fraction from TPA-treated HL-60 cells were analyzed for protein kinase C activity by consecutive column chromatography on Mono Q and hydroxyapatite. From both preparations two separate peaks of enzyme activity were obtained. The first peak, eluting at lower salt concentrations, is activated at lower TPA concentrations (3 X 10(-9) M) than the other (10(-7) M), which was eluted at higher salt concentrations.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0014-5793
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
5
|
| pubmed:volume |
249
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
264-6
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2737287-Animals,
pubmed-meshheading:2737287-Cell Line,
pubmed-meshheading:2737287-Chromatography, Liquid,
pubmed-meshheading:2737287-Dose-Response Relationship, Drug,
pubmed-meshheading:2737287-Enzyme Activation,
pubmed-meshheading:2737287-Isoenzymes,
pubmed-meshheading:2737287-Mice,
pubmed-meshheading:2737287-Protein Kinase C,
pubmed-meshheading:2737287-Tetradecanoylphorbol Acetate
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
Two isozymes of PKC found in HL-60 cells show a difference in activation by the phorbol ester TPA.
|
| pubmed:affiliation |
Institute of Biochemistry, German Cancer Research Center, Heidelberg.
|
| pubmed:publicationType |
Journal Article
|