Linked Life Data

2737163

Source:http://linkedlifedata.com/resource/pubmed/id/2737163

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-8-2
pubmed:abstractText
Localization of mast cells in the testis and ability of histamine (HA) to stimulate testicular testosterone (T) production in vitro were examined in gonadally active adult golden hamsters, kept under a long daily photoperiod (LD) and in gonadally regressed adult golden hamsters exposed to an inhibitory short photoperiod (SD). In both groups mast cells were present in the capsule of the testes and occasionally in vicinity of intratesticular blood vessels. Histamine stimulated T production in a dose dependent manner in incubations of regressed testes of SD animals, but had no stimulatory effect in the active testes of LD animals. In the incubations of SD testes, the effects of HA were abolished by the H-1 antagonist pyrilamine, but unaffected by the H-2 antagonist cimetidine. In both groups, HA enhanced the stimulatory effects of hCG. These results indicate that HA has steroidogenic activity in the testis and may be a factor involved in the regulation of Leydig cell function.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0013-7227
pubmed:author
pubmed:issnType
Print
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
560-2
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Histamine affects testicular steroid production in the golden hamster.
pubmed:affiliation
Department of Physiology, School of Medicine, Southern Illinois University, Carbondale 62901-6512.
pubmed:publicationType
Journal Article, In Vitro, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't