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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1989-7-25
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pubmed:abstractText |
Single K+ channels were studied using the patch-clamp method. A potential-dependent K+ channel of large conductance (about 100 pS at 100 mM of KCl on both membrane sides) was detected. Some properties of the channel (current-voltage relations, kinetic parameters, etc.) are presented. The channel was found to have about 16 resolvable quantized conductance substates. The data are confirmed by spontaneous channel degradation, i.e., spontaneous splitting of the channel conductance into independent conductance oligomers. Some properties of the conductance oligomers of different order are described. The degree of potential dependency of the conductance oligomer parameters is a function of potential dependency. The data obtained are in agreement with a hypothesis that the channels studied are clusters (aggregates) of elementary channel subunits.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
pubmed:issn |
0006-3002
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
6
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pubmed:volume |
981
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2730910-Animals,
pubmed-meshheading:2730910-Electric Conductivity,
pubmed-meshheading:2730910-Kinetics,
pubmed-meshheading:2730910-Macromolecular Substances,
pubmed-meshheading:2730910-Membrane Potentials,
pubmed-meshheading:2730910-Membrane Proteins,
pubmed-meshheading:2730910-Neuroglia,
pubmed-meshheading:2730910-Potassium,
pubmed-meshheading:2730910-Potassium Channels,
pubmed-meshheading:2730910-Snails
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pubmed:year |
1989
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pubmed:articleTitle |
Single potential-dependent K+ channels and their oligomers in molluscan glial cells.
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pubmed:affiliation |
Institute of Biological Physics, USSR Academy of Sciences, Pushchino.
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pubmed:publicationType |
Journal Article,
In Vitro
|