Linked Life Data

2730626

Source:http://linkedlifedata.com/resource/pubmed/id/2730626

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1989-7-6
pubmed:abstractText
Grant et al. have demonstrated that after caffeine intake the ratio of 1-methyluric acid (MU) and 1-methylxanthine (MX) in the urine indicates the total xanthine oxidase (XO) activity of the organism. It has been stated - after having applied this method on premature infants with severe respiration distress syndrome (17 cases) and on children in need of intensive care (18 cases) in the critical phase and during the reparation of the same patients as well, furthermore on so-called shock-tolerant patients (6 cases) and on healthy children (15 cases) - that the total XO activity can increase extremely in severe acute clinical states but a considerable decrease can be detected during reparation while in shock-tolerant states it can become expressively low. The investigations explain properly the favourable XO inhibiting effect of allopurinol demonstrated in states of experimental and clinical shock. The low XO activity observed in shock-tolerant conditions may be the result of intrinsic compensatory mechanisms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0232-766X
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S31-5
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Measurement of urinary caffeine metabolites reflecting the "in vivo" xanthine oxidase activity in premature infants with RDS and in hypoxic states of children.
pubmed:affiliation
Albert Szent-Györgyi University Medical School, Department of Paediatrics, Szeged, Hungary.
pubmed:publicationType
Journal Article