Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1989-7-6
pubmed:abstractText
Contrary to rats, developing guinea pigs don't react with a hypertrophy of their hearts following sublethal chronical intoxication with CO (200 ppm in room air applied to the pregnant mothers and subsequently to the infant animals). Since birth weight and postnatal growth remained in normal ranges, tissue oxygenation must have been sufficient despite a concentration of 30 +/- 4.5% COHb. Hence, ECGs didn't show characteristic parameters of heart hypertrophy. However, alterations of QRS vector loops consist in a more pronounced but retarded rightward accentuation during the first 4 days of life and afterwards in an accelerated turnover to the left relative to controls. We suppose a pathological volume loading of both the ventricles during the first week of postnatal life, caused by the chronically acting hypoxia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0232-766X
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S118-21
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Effect of mild chronic hypoxia on the infantile heart: ECGs of guinea pigs pre- and postnatally treated with carbon monoxide.
pubmed:affiliation
Institute of Pathophysiology, Karl Marx University, Leipzig, GDR.
pubmed:publicationType
Journal Article