rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6 Pt 1
|
pubmed:dateCreated |
1989-7-6
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pubmed:abstractText |
High doses of inhaled albuterol produce substantial improvements in bronchodilatation but are associated with dose-related systemic side effects including hypokalemia and hypomagnesemia. Concomitant diuretic therapy also produces these metabolic sequelae and may therefore precipitate cardiac arrhythmias in patients taking this combination of drugs. The purpose of this study was to investigate the electrocardiographic (ECG) effects of high-dose inhaled albuterol, and to evaluate whether potentiation occurs with bendrofluazide.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
|
pubmed:issn |
0002-9343
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
653-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2729315-Administration, Inhalation,
pubmed-meshheading:2729315-Adult,
pubmed-meshheading:2729315-Albuterol,
pubmed-meshheading:2729315-Bendroflumethiazide,
pubmed-meshheading:2729315-Blood Pressure,
pubmed-meshheading:2729315-Creatinine,
pubmed-meshheading:2729315-Diuretics,
pubmed-meshheading:2729315-Dose-Response Relationship, Drug,
pubmed-meshheading:2729315-Drug Evaluation,
pubmed-meshheading:2729315-Drug Synergism,
pubmed-meshheading:2729315-Electrocardiography,
pubmed-meshheading:2729315-Electrolytes,
pubmed-meshheading:2729315-Female,
pubmed-meshheading:2729315-Heart Rate,
pubmed-meshheading:2729315-Humans,
pubmed-meshheading:2729315-Hypokalemia,
pubmed-meshheading:2729315-Male
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pubmed:year |
1989
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pubmed:articleTitle |
Prior treatment with diuretic augments the hypokalemic and electrocardiographic effects of inhaled albuterol.
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pubmed:affiliation |
Department of Clinical Pharmacology, Ninewells Hospital and Medical School, Dundee, Scotland, United Kingdom.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|