Linked Life Data

2717227

Source:http://linkedlifedata.com/resource/pubmed/id/2717227

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-6-19
pubmed:abstractText
The severity of neurogenic damage to the gastric mucosa (GM) induced by emotional stress (ES) in administration of serotonin or its precursor in biosynthesis--5-hydroxytryptophan into the lateral ventricle of the brain was studied in experiments on mice of inbred strains. The development of lesions in the GM in the form of erosions and hemorrhages proved to be dependent on many factors, first of all on the time of administration of the preparations--before or after ES. The effect of 5-hydroxytryptophan on the formation of GM stress damage was less marked than that of serotonin. The intensifying effect of exogenous serotonin on post-stress GM damage was mainly manifested in the spring, which is associated with ES induced activation of the brain serotonergic system. The effect of exogenous serotonin on the degree of the neurogenous damage to the GM caused by ES is determined to a great measure by the genotype differences in the sensitivity of the central serotonergic mechanisms to the stimulating effect.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0031-2991
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
28-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Central serotonin administration and post-stress damage of the gastric mucosa in inbred mice during various seasons].
pubmed:publicationType
Journal Article, English Abstract