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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-6-9
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pubmed:abstractText |
Cerebral palsy (CP) is often a consequence of a hypoxic-ischemic encephalopathy and/or intracerebral hemorrhage secondary to pre- and peri-natal asphyxia. Hypodense lesions on the CT-scan are found in about 70 to 80% of CP-patients. In the present study, regional cerebral blood flow (CBF) was measured in CP-patients having a normal CT-scan. The aim was to correlate the CBF changes with the clinical and the etiologic findings. CBF was measured by xenon-133 inhalation and single photon emission computer tomography. The mean CBF value in 20 CP-patients, age 6-19 years, was 67 +/- 11 (1 SD) ml/100g/min, the same value as found in the 9 normal children. However, 16 of the 20 CP-patients had focal hypoperfused areas on the tomographic flow map. In the preterm infants (n = 7) the hypoperfused areas were mainly located in the posterior watershed areas, often in one hemisphere only. In the term infants (n = 13) both asymmetrical and symmetrical hypoperfused areas were observed in the anterior and posterior watershed areas. In addition, several children had larger low flow areas in the frontal and fronto-parietal lobes. In both groups, a relatively poor concordance was observed between the clinical findings and the expected location of the low flow area.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0174-304X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-40
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pubmed:dateRevised |
2008-1-16
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pubmed:meshHeading |
pubmed-meshheading:2716964-Adolescent,
pubmed-meshheading:2716964-Adult,
pubmed-meshheading:2716964-Blood Flow Velocity,
pubmed-meshheading:2716964-Cerebral Palsy,
pubmed-meshheading:2716964-Cerebrovascular Circulation,
pubmed-meshheading:2716964-Child,
pubmed-meshheading:2716964-Female,
pubmed-meshheading:2716964-Humans,
pubmed-meshheading:2716964-Image Processing, Computer-Assisted,
pubmed-meshheading:2716964-Infant, Newborn,
pubmed-meshheading:2716964-Infant, Premature,
pubmed-meshheading:2716964-Male,
pubmed-meshheading:2716964-Tomography, X-Ray Computed
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pubmed:year |
1989
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pubmed:articleTitle |
Cerebral blood flow abnormalities in cerebral palsied children with a normal CT scan.
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pubmed:affiliation |
Department of Pediatrics, State University Hospital, Rigshospitalet, Copenhagen, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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