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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1989-6-14
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pubmed:abstractText |
Four hundred and thirty-eight patients with biopsy-proven benign breast disease were followed annually in a prospective manner for 4-17 years, to analyze breast cancer risk, correlations with cancer development and recurrence during follow-up. Twelve breast cancers developed in 12 patients during follow-up, giving a 2.6 fold increased cancer risk over the reference population. No association was found between patients who developed cancer and those who did not with respect to the initial histologic feature (p = 0.9), the age at entry by decades (p = 0.4) and relative to menopause (p = 0.3), the presence of cysts (p = 0.5) or calcification (p = 0.2) in the biopsy specimen, a family history of breast cancer (p = 0.7) or the follow-up time (p = 0.9). Benign breast disease does not inevitably lead to recurrence. Moreover, 47% of the 438 patients never had any recurrence and were free of symptoms during follow-up, and 84% never required a further operation. We conclude that an aggressive approach to benign breast disease is not justified, for any type of lesion as defined in this report.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0018-0181
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
541-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2715018-Adenofibroma,
pubmed-meshheading:2715018-Biopsy,
pubmed-meshheading:2715018-Breast,
pubmed-meshheading:2715018-Breast Neoplasms,
pubmed-meshheading:2715018-Female,
pubmed-meshheading:2715018-Fibrocystic Breast Disease,
pubmed-meshheading:2715018-Follow-Up Studies,
pubmed-meshheading:2715018-Humans,
pubmed-meshheading:2715018-Lipoma,
pubmed-meshheading:2715018-Neoplasm Recurrence, Local,
pubmed-meshheading:2715018-Risk Factors
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pubmed:year |
1989
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pubmed:articleTitle |
[How great is the risk of cancer and recurrence following benign breast biopsy?].
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pubmed:publicationType |
Journal Article,
English Abstract
|