rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1989-6-16
|
pubmed:abstractText |
Long-term low-frequency stimulation (up to 120 days) of rabbit fast-twitch tibialis anterior muscle led, in a first-order-like time course, to changes in enzyme activities of energy metabolism which became stable with ongoing stimulation after 50 days. The glycolytic enzymes decreased to 30-40% of their normal values, but remained 2-3-fold higher than in heart or soleus muscle. The LDH isozyme pattern ultimately resembled that of the slow-twitch soleus muscle. Citrate synthase activity increased 3.7-fold which brought this enzyme to a value 45% above that of heart. These results indicate that chronic stimulation does not simply convert the fast-twitch muscle into a soleus-like slow-twitch muscle, but creates a tissue of unique metabolic properties.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0014-5793
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
24
|
pubmed:volume |
247
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
471-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2714446-Animals,
pubmed-meshheading:2714446-Citrate (si)-Synthase,
pubmed-meshheading:2714446-Electric Stimulation,
pubmed-meshheading:2714446-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:2714446-Energy Metabolism,
pubmed-meshheading:2714446-Glyceraldehyde-3-Phosphate Dehydrogenases,
pubmed-meshheading:2714446-Glycolysis,
pubmed-meshheading:2714446-Isoenzymes,
pubmed-meshheading:2714446-Kinetics,
pubmed-meshheading:2714446-L-Lactate Dehydrogenase,
pubmed-meshheading:2714446-Malate Dehydrogenase,
pubmed-meshheading:2714446-Male,
pubmed-meshheading:2714446-Muscles,
pubmed-meshheading:2714446-Myocardium,
pubmed-meshheading:2714446-Rabbits
|
pubmed:year |
1989
|
pubmed:articleTitle |
Chronic long-term electrostimulation creates a unique metabolic enzyme profile in rabbit fast-twitch muscle.
|
pubmed:affiliation |
Fakultät für Biologie, Universität Konstanz, FRG.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|