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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1989-6-14
|
| pubmed:abstractText |
The pharmacokinetics of soluble oral prednisolone were studied during induction therapy in six children with acute lymphoblastic leukaemia. There was a three- to four-fold variation in the pharmacokinetics of total and free prednisolone. For total prednisolone, the mean elimination half-life was relatively short (1.37 h) and the total clearance, relatively high (15.1 ml min-1 kg-1). The mean free fraction was high (0.37).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0344-5704
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
23
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
392-4
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:2713960-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:2713960-Child,
pubmed-meshheading:2713960-Child, Preschool,
pubmed-meshheading:2713960-Female,
pubmed-meshheading:2713960-Half-Life,
pubmed-meshheading:2713960-Humans,
pubmed-meshheading:2713960-Male,
pubmed-meshheading:2713960-Precursor Cell Lymphoblastic Leukemia-Lymphoma,
pubmed-meshheading:2713960-Prednisolone,
pubmed-meshheading:2713960-Prednisone
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
Pharmacokinetics of prednisolone in children with acute lymphoblastic leukaemia.
|
| pubmed:affiliation |
Department of Paediatrics and Child Health, St. Jame's University Hospital, Leeds, U.K.
|
| pubmed:publicationType |
Journal Article
|