Linked Life Data

2711742

Source:http://linkedlifedata.com/resource/pubmed/id/2711742

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-5-26
pubmed:abstractText
Experimental results, substantiating the idea of a specific mechanism for the activation of small-intestinal smooth muscle by the adrenergic system are summarized. This mechanism is realized via catecholamines affecting excitatory beta-adrenoreceptors located on cholinergic interneurones of the myenteric plexus. The excitatory beta-adrenoreceptors are shown to contribute to the realization of small-intestinal motor responses to acetylcholine, vagal stimulation and 5-hydroxytryptamine, histamine, bradykinin. The data obtained are an evidence of physiological significance of this specific adrenosensitive input of small-intestinal cholinergic neurones. The cholinergic neurones are shown to participate in producing small-intestinal responses to 5-hydroxytryptamine, histamine, bradykinin, the responses being, for this reason, dependent on the level of catecholamines, stimulating excitatory beta-adrenoreceptors. It is suggested that cholinergic neurones of the enteric nervous system are under double adrenergic control: a stimulating effect of catecholamines mediated by excitatory beta-adrenoreceptors is counteracted by an inhibitory effect of alpha-adrenoreceptor activation by sympathetic neuromediator noradrenaline.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0002-3027
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
45-53
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[The mechanism coupling adrenergic and cholinergic influences on the smooth musculature of the small intestine].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract