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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1978-2-18
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pubmed:abstractText |
We have previously reported on two patients with acute promyelocytic leukemia (APL) who had what appeared to be a deletion of chromosome No. 17. We now describe a third patient with APL. All three patients had a structural rearrangement involving No. 15 and No. 17. Our current interpretation of the chromosomal abnormality is that it is a reciprocal translocation, t (15;17) (q22; q21). Evidence that this is a consistent rearrangement associated with APL comes not only from our three patients, but also from two other published cases of APL, studied with banding, who also had an identical abnormality.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0020-7136
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
869-72
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:271143-Adult,
pubmed-meshheading:271143-Chromosome Deletion,
pubmed-meshheading:271143-Chromosomes, Human, 16-18,
pubmed-meshheading:271143-Chromosomes, Human, 21-22 and Y,
pubmed-meshheading:271143-Humans,
pubmed-meshheading:271143-Leukemia, Myeloid, Acute,
pubmed-meshheading:271143-Male,
pubmed-meshheading:271143-Translocation, Genetic
|
pubmed:year |
1977
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pubmed:articleTitle |
Further evidence for a non-random chromosomal abnormality in acute promyelocytic leukemia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Case Reports
|