| pubmed-article:2711402 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2711402 | lifeskim:mentions | umls-concept:C0035569 | lld:lifeskim |
| pubmed-article:2711402 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:2711402 | lifeskim:mentions | umls-concept:C0221102 | lld:lifeskim |
| pubmed-article:2711402 | lifeskim:mentions | umls-concept:C0600688 | lld:lifeskim |
| pubmed-article:2711402 | lifeskim:mentions | umls-concept:C1704711 | lld:lifeskim |
| pubmed-article:2711402 | pubmed:issue | 1-2 | lld:pubmed |
| pubmed-article:2711402 | pubmed:dateCreated | 1989-5-31 | lld:pubmed |
| pubmed-article:2711402 | pubmed:abstractText | The distribution and excretion of the plant toxin ricin were studied in rats after intravenous injection. 125I-labelled ricin was equal in toxicity to native ricin. Following injection, the liver was the major organ of localisation - 46% of injected dose at 0.5 h. The spleen and muscle were next with 9.9% and 13%, respectively, at 0.5 h. Ricin was relatively concentrated in the spleen (33% of injected dose/g of tissue) compared with the liver (7.4%/g) and the bone marrow (5.5%/g). The concentration in the lymph nodes was very low (1.2%/g). Ricin was quickly cleared from the animal; only 11% of the initial radioactivity remained 24 h later with 70% excreted in the urine. Excretion into the intestine via the bile duct was less than 5% by 24 h, 10-12% of the radioactivity was found in the intestinal contents or intestinal wall between 3 h and 12 h, and much of this was reabsorbed since less than 2% was recovered in faeces. | lld:pubmed |
| pubmed-article:2711402 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2711402 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2711402 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2711402 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2711402 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2711402 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:2711402 | pubmed:issn | 0300-483X | lld:pubmed |
| pubmed-article:2711402 | pubmed:author | pubmed-author:BellE BEB | lld:pubmed |
| pubmed-article:2711402 | pubmed:author | pubmed-author:DraysonM TMT | lld:pubmed |
| pubmed-article:2711402 | pubmed:author | pubmed-author:RamsdenC SCS | lld:pubmed |
| pubmed-article:2711402 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2711402 | pubmed:volume | 55 | lld:pubmed |
| pubmed-article:2711402 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2711402 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2711402 | pubmed:pagination | 161-71 | lld:pubmed |
| pubmed-article:2711402 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
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| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:meshHeading | pubmed-meshheading:2711402-... | lld:pubmed |
| pubmed-article:2711402 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2711402 | pubmed:articleTitle | The toxicity, distribution and excretion of ricin holotoxin in rats. | lld:pubmed |
| pubmed-article:2711402 | pubmed:affiliation | Department of Cell and Structural Biology, Medical School, University of Manchester, U.K. | lld:pubmed |
| pubmed-article:2711402 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2711402 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2711402 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2711402 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2711402 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2711402 | lld:pubmed |
