pubmed-article:2710202 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:2710202 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:2710202 | lifeskim:mentions | umls-concept:C0031809 | lld:lifeskim |
pubmed-article:2710202 | lifeskim:mentions | umls-concept:C0205127 | lld:lifeskim |
pubmed-article:2710202 | lifeskim:mentions | umls-concept:C0231221 | lld:lifeskim |
pubmed-article:2710202 | lifeskim:mentions | umls-concept:C0449774 | lld:lifeskim |
pubmed-article:2710202 | pubmed:issue | 19 | lld:pubmed |
pubmed-article:2710202 | pubmed:dateCreated | 1989-5-30 | lld:pubmed |
pubmed-article:2710202 | pubmed:abstractText | Although most asymptomatic patients with the Wolff-Parkinson-White electrocardiographic pattern have a good prognosis, some die suddenly. The mechanism of sudden death is usually ventricular fibrillation, which is triggered by atrial fibrillation with a rapid ventricular response rate. Electrophysiologic testing has been proposed to identify asymptomatic patients who may be at risk for sudden death. Meaningful application of such testing requires a knowledge of whether the electrophysiologic measurements are reproducible over time. Consequently, we performed electrophysiologic studies on two occasions at least 36 months apart (mean +/- SD, 54.7 +/- 14) in 29 asymptomatic patients with the pattern. Twenty-seven patients remained asymptomatic, and sustained supraventricular tachycardia developed in two during the follow-up period. Nine patients (31 percent) lost the capacity for preexcitation and anterograde conduction over the accessory pathway, which produces the Wolff-Parkinson-White pattern. The others had little change in measurements of conduction over the accessory pathway. Patients who lost conduction over the accessory pathway tended to be older (mean +/- SD, 50 +/- 18 vs. 39 +/- 11 years; P = 0.06) than patients who retained preexcitation, and they had longer anterograde effective refractory periods at the first assessment (414 +/- 158 vs. 295 +/- 27 msec; P = 0.003). We conclude that a considerable number of asymptomatic patients with the Wolff-Parkinson-White pattern lose their capacity for anterograde conduction over the accessory pathway. This loss of capacity probably contributes to the low mortality among asymptomatic patients. | lld:pubmed |
pubmed-article:2710202 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2710202 | pubmed:language | eng | lld:pubmed |
pubmed-article:2710202 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:2710202 | pubmed:citationSubset | AIM | lld:pubmed |
pubmed-article:2710202 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:2710202 | pubmed:month | May | lld:pubmed |
pubmed-article:2710202 | pubmed:issn | 0028-4793 | lld:pubmed |
pubmed-article:2710202 | pubmed:author | pubmed-author:YeeRR | lld:pubmed |
pubmed-article:2710202 | pubmed:author | pubmed-author:KleinG JGJ | lld:pubmed |
pubmed-article:2710202 | pubmed:author | pubmed-author:SharmaA DAD | lld:pubmed |
pubmed-article:2710202 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:2710202 | pubmed:day | 11 | lld:pubmed |
pubmed-article:2710202 | pubmed:volume | 320 | lld:pubmed |
pubmed-article:2710202 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:2710202 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:2710202 | pubmed:pagination | 1229-33 | lld:pubmed |
pubmed-article:2710202 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:2710202 | pubmed:year | 1989 | lld:pubmed |
pubmed-article:2710202 | pubmed:articleTitle | Longitudinal electrophysiologic assessment of asymptomatic patients with the Wolff-Parkinson-White electrocardiographic pattern. | lld:pubmed |
pubmed-article:2710202 | pubmed:affiliation | Clinical Electrophysiology Laboratory, University Hospital, London, ON, Canada. | lld:pubmed |
pubmed-article:2710202 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:2710202 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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