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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1989-6-7
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pubmed:abstractText |
A beta-lactam-sensitive strain of Staphylococcus aureus could be converted to methicillin resistance by the introduction of a plasmid carrying the 4.3-kilobase HindIII chromosomal DNA fragment which encoded the mecA gene from a methicillin-resistant S. aureus. Transformant cells produced methicillin-resistant S. aureus-specific penicillin-binding protein constitutively, and additional insertion of an inducible penicillinase plasmid caused production of the pencillin-binding protein to become inducible.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-107388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-2826391,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-2985470,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3003024,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3031442,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3096969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3221195,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3305073,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3488015,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3499861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3638304,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3848293,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3848294,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-3878127,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-6389538,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-6563036,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2708325-666295
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0021-9193
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
171
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2882-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:2708325-Bacterial Proteins,
pubmed-meshheading:2708325-Carrier Proteins,
pubmed-meshheading:2708325-Cloning, Molecular,
pubmed-meshheading:2708325-Gene Expression Regulation,
pubmed-meshheading:2708325-Hexosyltransferases,
pubmed-meshheading:2708325-Muramoylpentapeptide Carboxypeptidase,
pubmed-meshheading:2708325-Penicillin Resistance,
pubmed-meshheading:2708325-Penicillin-Binding Proteins,
pubmed-meshheading:2708325-Peptidyl Transferases,
pubmed-meshheading:2708325-Staphylococcus aureus
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pubmed:year |
1989
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pubmed:articleTitle |
Expression and inducibility in Staphylococcus aureus of the mecA gene, which encodes a methicillin-resistant S. aureus-specific penicillin-binding protein.
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pubmed:affiliation |
Department of Clinical Pathology, Teikyo University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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