Linked Life Data

2708009

Source:http://linkedlifedata.com/resource/pubmed/id/2708009

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-5-26
pubmed:abstractText
Following inoculation of chimpanzees, the human immunodeficiency virus (HIV) establishes a long-term persistent infection characterized by seroconversion and the presence in peripheral blood cells of recoverable virus which can be quantitated. Because most HIV-infected chimpanzees have developed no signs of clinical diseases or hematologic abnormalities, their virologic, serologic and other immune responses can be compared with those of asymptomatic HIV-infected persons. This analysis might lead to the identification of factors important in preventing the development of disease. There are now approximately 100 HIV-infected chimpanzees in the United States, and many of these animals could be made available for testing chemotherapeutic agents for the ability to alter virus load or to enhance immune responses.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5526
pubmed:author
pubmed:issnType
Print
pubmed:volume
30 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
HIV infection of chimpanzees as a model for testing chemotherapeutics.
pubmed:affiliation
Yerkes Regional Primate Research Center, Atlanta, Ga.30322.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.