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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1989-6-2
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pubmed:abstractText |
Conventional and fluorescence videomicroscopy using Na-fluorescein as tracer was performed in 13 patients with rheumatoid arthritis (RA) and Waaler Rose titers less than 1: 112, 10 patients with titers greater than or equal to 1: 112 and 11 patients with osteoarthritis (OA) (control group). At the nailfold different microvascular diameters, capillary flow pattern, red blood cell velocity and transcapillary diffusion of Na-fluorescein were determined. Mean red blood cell velocity was significantly (p less than 0.02) decreased in patients with RA and high titers (0.23 +/- 0.21 0.21 mm/s) when compared to OA patients (0.59 +/- 0.20 mm/s). Abnormal flow patterns, in 2 cases even a reversal of flow direction, were only observed in RA patients and not in controls. Mean transcapillary and interstitial diffusion of Na-fluorescein was not enhanced at the nailfold in RA-patients. These findings do not exclude increased microvascular permeability in synovial membranes or in RA patients with vasculitis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-53
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2706819-Adult,
pubmed-meshheading:2706819-Aged,
pubmed-meshheading:2706819-Arthritis, Rheumatoid,
pubmed-meshheading:2706819-Capillaries,
pubmed-meshheading:2706819-Female,
pubmed-meshheading:2706819-Humans,
pubmed-meshheading:2706819-Male,
pubmed-meshheading:2706819-Microscopy, Fluorescence,
pubmed-meshheading:2706819-Middle Aged,
pubmed-meshheading:2706819-Nails,
pubmed-meshheading:2706819-Osteoarthritis,
pubmed-meshheading:2706819-Videotape Recording
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pubmed:articleTitle |
Microvascular dynamics at the nailfold in rheumatoid arthritis.
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pubmed:affiliation |
Department of Rheumatology, University of Ancona, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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