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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1989-6-8
|
| pubmed:abstractText |
The patch-clamp technique has been applied to the somatic membrane of the leech AP neurons. Ionic currents from single potassium channels were recorded in inside-out configuration. Two types of channels, sharing close values of conductance in symmetrical K+, were identified as distinct, according to their properties of rectification, Ca2+ sensitivity and voltage dependence. The channels designated as VCI exhibited an outward rectification and their gating was quite independent on changes of patch potential and of [Ca2+]i. The channels designated as VCD showed a linear I-V relationship and their activity was dependent on both the membrane potential and the intracellular [Ca2+].
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0006-8993
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
3
|
| pubmed:volume |
483
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
294-300
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1989
|
| pubmed:articleTitle |
Two types of K+ channels in excised patches of somatic membrane of the leech AP neuron.
|
| pubmed:affiliation |
Dipartimento di Fisiologia e Biochimica, Universitá di Pisa, Italy.
|
| pubmed:publicationType |
Journal Article,
In Vitro
|