Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-6-8
pubmed:abstractText
Despite the frequent use of freon-22 (e.g. to measure pulmonary blood flow), there is no agreement on its solubility in water or body fluids. The values in the literature vary, often quoted without reference to measurement or identification as Ostwald or Bunsen coefficients. We used a Schölander apparatus and determined the Bunsen solubility coefficient (mlgas.(mlfluid.atmosphere)-1) at 37 degrees C as: 0.476 in water; 0.673 in human whole blood; 0.479 in human plasma; 0.662 in canine whole blood; 0.437 in canine plasma; and 1.077 in homogenized canine lung tissue. As pure freon was used, these solubilities may not be applicable if freon-22 does not obey Henry's law. In man, the Ostwald solubility coefficient is calculated as 0.76 ml/ml whole blood at BTPS. These results provide information for further studies involving freon-22, and clear the confusion which has arisen from poorly defined solubility coefficients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0007-0912
pubmed:author
pubmed:issnType
Print
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
425-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Solubility of freon-22 in blood and lung tissue.
pubmed:affiliation
Department of Human Sciences, Loughborough University of Technology.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't