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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1989-8-25
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pubmed:databankReference |
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pubmed:abstractText |
A novel type of alpha-amylase was detected in a lung carcinoid tissue after surveying the cDNA library constructed from this tumor mRNA. Nucleotide sequence analysis showed that the amylase expressed in this carcinoid tumor has 13 and 6 amino acid substitutions when compared with salivary amylase (Amy1) and pancreatic amylase (Amy2), respectively. The nucleotide sequence homologies of cDNAs between this carcinoid amylase and amy1, amy2 are 97.5% and 98.2%, respectively. The nucleotide sequence comparison strongly suggests that this new amylase is the product of the amy3 gene that has been detected in human genome [Emi et al., Gene 62 (1988) 229-235]
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0378-1119
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2701942-Amino Acid Sequence,
pubmed-meshheading:2701942-Base Sequence,
pubmed-meshheading:2701942-Carcinoid Tumor,
pubmed-meshheading:2701942-Cloning, Molecular,
pubmed-meshheading:2701942-Codon,
pubmed-meshheading:2701942-DNA,
pubmed-meshheading:2701942-DNA, Neoplasm,
pubmed-meshheading:2701942-DNA Probes,
pubmed-meshheading:2701942-Female,
pubmed-meshheading:2701942-Genes,
pubmed-meshheading:2701942-Humans,
pubmed-meshheading:2701942-Immunohistochemistry,
pubmed-meshheading:2701942-Isoenzymes,
pubmed-meshheading:2701942-Lung Neoplasms,
pubmed-meshheading:2701942-Middle Aged,
pubmed-meshheading:2701942-Molecular Sequence Data,
pubmed-meshheading:2701942-RNA, Messenger,
pubmed-meshheading:2701942-Restriction Mapping,
pubmed-meshheading:2701942-Sequence Homology, Nucleic Acid,
pubmed-meshheading:2701942-alpha-Amylases
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pubmed:year |
1989
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pubmed:articleTitle |
A novel type of human alpha-amylase produced in lung carcinoid tumor.
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pubmed:affiliation |
Institute for Molecular and Cellular Biology, Osaka University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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