Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1990-3-16
|
pubmed:abstractText |
The efficacy of cefaclor and of trimethoprim-sulfamethoxazole (TMP-SMX) in the management of recurrent otitis media was evaluated in a randomized single-blind controlled trial. The median age of the patients was 12 months (range 5-37); there were 37 boys and 19 girls. All had received 1 or more courses of antibacterials for acute otitis media in the previous 2-3 weeks. 27 were treated with oral cefaclor suspension, 40 mg/kg/day in 3 divided doses, and 29 with 1 mg/kg/day of TMP-SMX (trimethoprim 8 mg, sulfamethoxazole 40 mg) in 2 divided doses, each group for 10 days. 70% of the cefaclor group and 90% of the TMP-SMX group were cured after the 10 days of therapy (0.1 greater than p greater than 0.05). Results were not better on the 21st day as compared with the 10th. Our data indicate a mild preference for TMP-SMX (although p was not less than 0.05), since it needs to be given only twice a day and costs less than cefaclor.
|
pubmed:language |
heb
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0017-7768
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
117
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
361-3
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2695415-Acute Disease,
pubmed-meshheading:2695415-Cefaclor,
pubmed-meshheading:2695415-Cephalexin,
pubmed-meshheading:2695415-Child, Preschool,
pubmed-meshheading:2695415-Drug Therapy, Combination,
pubmed-meshheading:2695415-Female,
pubmed-meshheading:2695415-Humans,
pubmed-meshheading:2695415-Infant,
pubmed-meshheading:2695415-Male,
pubmed-meshheading:2695415-Otitis Media,
pubmed-meshheading:2695415-Randomized Controlled Trials as Topic,
pubmed-meshheading:2695415-Recurrence,
pubmed-meshheading:2695415-Single-Blind Method,
pubmed-meshheading:2695415-Trimethoprim-Sulfamethoxazole Combination
|
pubmed:year |
1989
|
pubmed:articleTitle |
[Cefaclor and trimethoprim-sulfamethoxazole for recurrent otitis media].
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract,
Randomized Controlled Trial
|