Linked Life Data

2694423

Source:http://linkedlifedata.com/resource/pubmed/id/2694423

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1990-3-9
pubmed:abstractText
Fibrinogen coupled to colloidal gold has proven to be a useful agent for probing the glycoprotein IIb-IIIa receptor on human and bovine platelets at the ultrastructural level. The reagent has helped to demonstrate fundamental differences in the reorganization of the fibrinogen receptors on human and cattle platelets following surface activation. However, commercial preparations of human fibrinogen have not yielded a stable reagent in our hands when coupled to colloidal gold. The present study has substituted bovine for human fibrinogen. Bovine fibrinogen gold proved to be a more stable reagent and could be substituted for human fibrinogen gold in all experiments on human and bovine platelets.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0340-6245
pubmed:author
pubmed:issnType
Print
pubmed:day
29
pubmed:volume
62
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1112-5
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Gold-labeled bovine fibrinogen for study of human platelets.
pubmed:affiliation
Department of Laboratory Medicine, University of Minnesota Medical School, Minneapolis 55455.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't