| pubmed-article:2688896 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2688896 | lifeskim:mentions | umls-concept:C0026900 | lld:lifeskim |
| pubmed-article:2688896 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:2688896 | lifeskim:mentions | umls-concept:C0029005 | lld:lifeskim |
| pubmed-article:2688896 | lifeskim:mentions | umls-concept:C1145667 | lld:lifeskim |
| pubmed-article:2688896 | lifeskim:mentions | umls-concept:C1515877 | lld:lifeskim |
| pubmed-article:2688896 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:2688896 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:2688896 | pubmed:dateCreated | 1990-2-7 | lld:pubmed |
| pubmed-article:2688896 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2688896 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2688896 | pubmed:abstractText | The v-myb oncogene induces myeloid leukemias in chickens, transforms myeloid cells in vitro, and encodes a sequence-specific DNA binding protein. We used differential hybridization to screen for v-myb-regulated genes in cells transformed by a temperature-sensitive mutant of the oncogene and identified a new gene, mim-1, which encodes a specifically expressed, secretable protein contained in the granules of both normal and v-myb-transformed promyelocytes. The promoter of the mim-1 gene contains three closely spaced binding sites for v-myb protein and is strongly activated by v-myb in a cotransfection assay. Synthetic copies of the binding sites are both necessary and sufficient to confer v-myb protein-dependent activation to a heterologous promoter. We conclude that mim-1 is a cellular gene that is directly regulated by the product of the v-myb oncogene. | lld:pubmed |
| pubmed-article:2688896 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2688896 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2688896 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2688896 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:2688896 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2688896 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:2688896 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:2688896 | pubmed:author | pubmed-author:GradJJ | lld:pubmed |
| pubmed-article:2688896 | pubmed:author | pubmed-author:NessS ASA | lld:pubmed |
| pubmed-article:2688896 | pubmed:author | pubmed-author:MarknellAA | lld:pubmed |
| pubmed-article:2688896 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2688896 | pubmed:day | 22 | lld:pubmed |
| pubmed-article:2688896 | pubmed:volume | 59 | lld:pubmed |
| pubmed-article:2688896 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2688896 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2688896 | pubmed:pagination | 1115-25 | lld:pubmed |
| pubmed-article:2688896 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:2688896 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2688896 | pubmed:articleTitle | The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene. | lld:pubmed |
| pubmed-article:2688896 | pubmed:affiliation | Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Federal Republic of Germany. | lld:pubmed |
| pubmed-article:2688896 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2688896 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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