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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1990-1-25
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pubmed:abstractText |
The time and site of expression of five antigens, recognized by monoclonal antibodies raised against blood-stage parasites, were studied in the exoerythrocytic stage of Plasmodium berghei using indirect immunofluorescent antibody staining. Two monoclonal antibodies (W 3.5, I 2.6), which stain the cytoplasm of infected erythrocytes, did not stain the cytoplasm of the infected liver cell but stained the parasite itself suggesting a difference in the antigenic architecture of the erythrocytic and exoerythrocytic parasites. Another antibody (17.6.1) revealed a further difference in the antigenic composition of the blood and liver-stage parasites being expressed almost exclusively in the former. Two others (C139 and 17.3.9) showed broadly similar patterns of expression in these two stages of the malarial life-cycle.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0031-1820
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
99 Pt 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
165-70
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2687775-Animals,
pubmed-meshheading:2687775-Antibodies, Monoclonal,
pubmed-meshheading:2687775-Antigens, Protozoan,
pubmed-meshheading:2687775-Cell Line,
pubmed-meshheading:2687775-Erythrocytes,
pubmed-meshheading:2687775-Fluorescent Antibody Technique,
pubmed-meshheading:2687775-Liver,
pubmed-meshheading:2687775-Mice,
pubmed-meshheading:2687775-Plasmodium berghei
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pubmed:year |
1989
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pubmed:articleTitle |
Contrasts in antigen expression in the erythrocytic and exoerythrocytic stages of rodent malaria.
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pubmed:affiliation |
Department of Pure and Applied Biology, Imperial College, London.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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